SCHEMBL25568579

SCHEMBL25568579

CC(C)CC(=O)c1ccnn1C1CCOC1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDE4D Q08499 3/20 0.43
MKNK1 Q9BUB5 1/20 0.35
MKNK2 Q9HBH9 1/20 0.35
POLB P06746 1/20 0.35
FPR1 P21462 1/20 0.35
SRC P12931 1/20 0.35
OPRM1 P35372 3/20 0.34
PDE1A P54750 1/20 0.34
PDE1B Q01064 1/20 0.34
PDE1C Q14123 1/20 0.34
KMT2A Q03164 1/20 0.34
SPR P35270 1/20 0.34
HTR3A P46098 3/20 0.33
KDM4C Q9H3R0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22125893 0.79 OPRM1 (0.40) MKNK1MKNK2POLBSRCOPRM1
SCHEMBL22366382 0.79 KDM4C (0.42) POLBSRCOPRM1KMT2ASPR
SCHEMBL25564438 0.77 CNR2 (0.39) PDE4DPOLBFPR1SRCOPRM1
SCHEMBL22319884 0.77 F2 (0.40) POLBSRCOPRM1PDE1APDE1B
SCHEMBL20229800 0.77 HSD11B1 (0.41) PDE4DPOLBPDE1APDE1BPDE1C
SCHEMBL17452638 0.75 MAPK1 (0.39) FPR1PDE1APDE1BPDE1CKMT2A
SCHEMBL25562690 0.72 CNR2 (0.39) POLBFPR1SRCOPRM1PDE1A
SCHEMBL17454459 0.72 PIK3CD (0.38) KMT2A
SCHEMBL29629580 0.71 OPRM1 (0.43) POLBSRCOPRM1KMT2AKDM4C
SCHEMBL29629564 0.71 KDM4C (0.41) POLBOPRM1KMT2AKDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159465-A1 IMMUNOMODULATOR HITGEN INC. (CN) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159465-A1 IMMUNOMODULATOR IL2, IL17A, IL2RA PDE4D 2474/4885MKNK1 3472/4885MKNK2 3492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.