Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10496198 | 0.85 | KMT2A (0.63) | KMT2AMEN1SLC6A2SLC6A4HTT | |
| SCHEMBL306171 | 0.79 | KMT2A (0.56) | KMT2AMEN1SLC6A2SLC6A4HTT | |
| SCHEMBL17877660 | 0.76 | KMT2A (0.54) | KMT2AMEN1SLC6A2SLC6A4HTT | |
| SCHEMBL30343474 | 0.76 | KMT2A (0.54) | KMT2AMEN1SLC6A2SLC6A4HTT | |
| SCHEMBL701691 | 0.76 | SIRT1 (0.60) | KMT2AMEN1HTTGAAHPGD | |
| SCHEMBL9669181 | 0.76 | HTT (0.55) | KMT2AMEN1HTTGAAHPGD | |
| Iodide SCHEMBL7710889 | 0.75 | SIRT1 (0.58) | KMT2AMEN1HTTGAAHPGD | |
| SCHEMBL9254635 | 0.75 | KDM4E (0.53) | KMT2AMEN1GAAHPGDALDH1A1 | |
| SCHEMBL29287849 | 0.75 | KDM4E (0.54) | KMT2AMEN1HTTGAAHPGD | |
| SCHEMBL6832097 | 0.75 | KMT2A (0.56) | KMT2AMEN1HTTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |