Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.38 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.34 |
| ▸ | ACHE | P22303 | 4/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.30 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.30 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23416766 | 1.00 | NCF1 (0.43) | NCF1SLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL19442433 | 0.90 | SLC6A1 (0.41) | NCF1SLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL4036508 | 0.90 | NCF1 (0.48) | NCF1GNAO1HRH3ACHEHRH4 | |
| SCHEMBL24881447 | 0.85 | NCF1 (0.48) | NCF1GNAO1HRH3ACHEHRH4 | |
| SCHEMBL18525560 | 0.83 | NCF1 (0.36) | NCF1GNAO1ACHE | |
| SCHEMBL22047606 | 0.82 | NCF1 (0.42) | NCF1GNAO1HRH3ACHEHRH4 | |
| SCHEMBL25565872 | 0.82 | GNAO1 (0.41) | NCF1SLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL5668144 | 0.80 | — | — | |
| SCHEMBL25570435 | 0.80 | SLC6A1 (0.48) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL757866 | 0.80 | NCF1 (0.62) | NCF1GNAO1HRH3ACHEHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |