Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561345 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL5022755 | 0.81 | ALDH1A1 (0.71) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL2559258 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL2885107 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL9853586 | 0.78 | L3MBTL1 (0.51) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL30268627 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL1159451 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL5026728 | 0.76 | ALDH1A1 (0.75) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL15416929 | 0.76 | ALDH1A1 (0.63) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL7366005 | 0.76 | ALDH1A1 (0.84) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011132051-A2 | TRICYCLE COMPOUNDS AS PHOSPHODIESTERASE-10 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2011-10-27 | — | — | WO | disclosed |