Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24027443 | 0.88 | GNAI3 (0.46) | SMN1; SMN2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL24793522 | 0.88 | BACE1 (0.37) | SMN1; SMN2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL20492763 | 0.85 | PABPC1 (0.45) | MEN1MAPTKMT2AEPHX1EPHX2 | |
| SCHEMBL23759700 | 0.85 | CARM1 (0.45) | SMN1; SMN2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL26022466 | 0.84 | GNAI3 (0.56) | EPHX2GNAI3GNAO1GNAI1 | |
| SCHEMBL22994955 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL2760188 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL5554376 | 0.82 | ACHE (0.41) | GNAI3GNAO1GNAI1CARM1PRMT6 | |
| SCHEMBL5316790 | 0.80 | KDM4E (0.44) | SMN1; SMN2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL21698460 | 0.80 | KDM4E (0.36) | SMN1; SMN2KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098730-A1 | COMPOUND CONTAINING CYCLOALKYL OR HALOALKYL | 正大天晴药业集团股份有限公司 | 2023-06-08 | — | — | WO | disclosed |