Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24925450 | 0.87 | ACHE (0.35) | ACHECHRM5ADRA2CAXLFLT3 | |
| SCHEMBL12464451 | 0.84 | ACHE (0.44) | ACHECHRM5ADRA2C | |
| SCHEMBL25575295 | 0.82 | SMN1; SMN2 (0.39) | GNAI3GNAO1GNAI1DRD4DRD3 | |
| SCHEMBL20492763 | 0.80 | PABPC1 (0.45) | GNAI3GNAO1GNAI1CARM1PRMT6 | |
| SCHEMBL4623536 | 0.75 | MEN1 (0.43) | GNAI3GNAO1GNAI1DRD4DRD3 | |
| SCHEMBL2842528 | 0.75 | ACHE (0.47) | ACHECHRM5ADRA2C | |
| SCHEMBL24793522 | 0.74 | BACE1 (0.37) | ACHEDRD4DRD3 | |
| SCHEMBL13654287 | 0.74 | GNAI3 (0.36) | ADRA2CGNAI3GNAO1GNAI1DRD4 | |
| SCHEMBL5909386 | 0.73 | GNAI3 (0.45) | ADRA2CGNAI3GNAO1GNAI1DRD4 | |
| SCHEMBL1678882 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006089076-A9 | THIAZOLE AMIDES, IMIDAZOLE AMIDES AND RELATED ANALOGUES | NEUROGEN CORP (US) | 2007-04-26 | — | — | WO | disclosed |