Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25575666 | 0.88 | ADRA1A (0.42) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL6014048 | 0.88 | ADRA1A (0.42) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL28779148 | 0.86 | ALDH1A1 (0.41) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL15775112 | 0.83 | KEAP1 (0.40) | ALDH1A1EPHX2HDAC8ADRA1AKEAP1 | |
| SCHEMBL12644382 | 0.81 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL30919638 | 0.80 | EPHX2 (0.44) | CHRM2CHRM4CHRM1CHRM3ACKR3 | |
| SCHEMBL30919801 | 0.80 | EPHX2 (0.44) | CHRM2CHRM4CHRM1CHRM3ACKR3 | |
| SCHEMBL30919837 | 0.80 | EPHX2 (0.44) | CHRM2CHRM4CHRM1CHRM3ACKR3 | |
| SCHEMBL25397689 | 0.79 | EPHX2 (0.45) | CHRM2CHRM4CHRM1CHRM3ACKR3 | |
| SCHEMBL20385914 | 0.79 | ADRA1A (0.49) | ALDH1A1SIGMAR1EPHX2ADRA1APRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109320502-B | Neurotensin receptor ligands | 3B制药有限公司 | 2022-06-07 | — | — | CN | disclosed |