SCHEMBL25585228

SCHEMBL25585228

COC(=O)[C@H]1[C@H]2CC/C=C\CC[C@@H]2[C@H]1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ PPM1B O75688 1/20 0.49
▸ PTPN1 P18031 1/20 0.49
▸ PPP1CC P36873 1/20 0.49
▸ RAB9A P51151 2/20 0.45
▸ NPC1 O15118 1/20 0.45
▸ POLB P06746 2/20 0.42
▸ TP53 P04637 1/20 0.36
▸ SLC6A3 Q01959 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ SLC6A4 P31645 1/20 0.33
▸ APEX1 P27695 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25585134 1.00 PPM1B (0.49) PPM1BPTPN1PPP1CCRAB9ANPC1
SCHEMBL26718276 1.00 PPM1B (0.49) PPM1BPTPN1PPP1CCRAB9ANPC1
SCHEMBL25585168 0.92 RAB9A (0.50) PPM1BPTPN1PPP1CCRAB9ANPC1
SCHEMBL25585142 0.84 POLB (0.44) RAB9ANPC1POLBTP53ALDH1A1
SCHEMBL25277941 0.82 PPM1B (0.53) PPM1BPTPN1PPP1CCPOLBTP53
SCHEMBL31010896 0.82 PPM1B (0.53) PPM1BPTPN1PPP1CCPOLBTP53
SCHEMBL31010895 0.82 PPM1B (0.53) PPM1BPTPN1PPP1CCPOLBTP53
SCHEMBL15647516 0.82 PPM1B (0.57) PPM1BPTPN1PPP1CCPOLBTP53
SCHEMBL15646197 0.82 PPM1B (0.57) PPM1BPTPN1PPP1CCPOLBTP53
SCHEMBL15645793 0.82 PPM1B (0.57) PPM1BPTPN1PPP1CCPOLBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167211-A1 MONOMER ISOMERIZATION AND POLYMER FLUORINATION FOR SUSTAINABLE DEPOLYMERIZABLE POLYMERS THE UNIVERSITY OF AKRON 2023-06-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167211-A1 MONOMER ISOMERIZATION AND POLYMER FLUORINATION FOR SUSTAINABLE DEPOLYMERIZABLE POLYMERS PFAS, PARG, MFAP1 PPM1B 4303/4885PTPN1 4774/4885PPP1CC 2494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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