Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17963082 | 0.83 | HCAR2 (0.40) | HCAR2RXRAP4HA1P4HTMMIF | |
| SCHEMBL31403685 | 0.80 | HCAR3 (0.41) | HCAR2RXRAP4HA1P4HTMMIF | |
| SCHEMBL31403687 | 0.80 | HCAR3 (0.41) | HCAR2RXRAP4HA1P4HTMMIF | |
| SCHEMBL14605287 | 0.79 | PTPN11 (0.34) | HCAR2P4HA1P4HTMMIFHCAR3 | |
| SCHEMBL20318948 | 0.78 | HCAR2 (0.36) | HCAR2RXRAP4HA1P4HTMMIF | |
| SCHEMBL13341877 | 0.76 | NOS3 (0.36) | KDM4E | |
| SCHEMBL24967186 | 0.75 | RXRA (0.34) | HCAR2RXRAP4HA1P4HTMMIF | |
| SCHEMBL31403567 | 0.75 | HSD17B10 (0.40) | HCAR2RXRAHCAR3HSD17B10SPR | |
| SCHEMBL15144409 | 0.71 | KDM4E (0.47) | HCAR3KDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL31632800 | 0.71 | SCN2B (0.49) | RXRAALDH1A1PTPN11SPRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4183786-A1 | DERIVATIVES OF QUINOLINES AS INHIBITORS OF DYRK1A AND/OR DYRK1B KINASES | Felicitex Therapeutics, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |