Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 10/20 | 0.39 |
| ▸ | MMP9 | P14780 | 10/20 | 0.39 |
| ▸ | MMP8 | P22894 | 6/20 | 0.39 |
| ▸ | MMP12 | P39900 | 6/20 | 0.39 |
| ▸ | MMP14 | P50281 | 6/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 2/20 | 0.35 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.35 |
| ▸ | GGH | Q92820 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12580525 | 0.90 | FOLH1 (0.42) | ALDH1A1MMP2MMP9MMP8MMP12 | |
| SCHEMBL14519219 | 0.84 | MMP2 (0.52) | ALDH1A1MMP2MMP9MMP8MMP12 | |
| SCHEMBL13498182 | 0.84 | GLP1R (0.44) | ALDH1A1MMP2MMP9MMP8MMP12 | |
| SCHEMBL71800 | 0.83 | FOLH1 (0.43) | ALDH1A1FOLH1NOD1RIMKLANAALAD2 | |
| SCHEMBL22111315 | 0.83 | FOLH1 (0.43) | ALDH1A1FOLH1NOD1RIMKLANAALAD2 | |
| SCHEMBL12118214 | 0.83 | FOLH1 (0.43) | ALDH1A1FOLH1NOD1RIMKLANAALAD2 | |
| SCHEMBL14118034 | 0.83 | FOLH1 (0.51) | ALDH1A1MMP2MMP9MMP8MMP12 | |
| SCHEMBL22134382 | 0.83 | LMNA (0.48) | ALDH1A1MMP2MMP9MMP8MMP12 | |
| SCHEMBL21440847 | 0.81 | NOD1 (0.36) | ALDH1A1MMP2MMP9MMP8MMP12 | |
| SCHEMBL22026231 | 0.81 | MMP2 (0.54) | MMP2MMP9MMP8MMP12MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023108009-A1 | COMPOUNDS SPECIFIC TO GRANZYME B AND USES THEREOF | CYTOSITE BIOPHARMA INC. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023108031-A1 | PRODRUGS FOR COMPOUNDS SPECIFIC TO GRANZYME B AND USES THEREOF | CYTOSITE BIOPHARMA INC. (US) | 2023-06-15 | — | — | WO | disclosed |