Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25590680 | 0.80 | MAPT (0.41) | MAPTTRPV1NR3C1AHRMEN1 | |
| SCHEMBL25590686 | 0.80 | TRPV1 (0.46) | MAPTTRPV1NR3C1AHRMEN1 | |
| SCHEMBL25591484 | 0.78 | MAPT (0.46) | MAPTTRPV1NR3C1AHRMEN1 | |
| SCHEMBL25592034 | 0.77 | NR3C1 (0.48) | MAPTTRPV1NR3C1AHRMEN1 | |
| SCHEMBL25590396 | 0.77 | CSF1R (0.53) | MAPTTRPV1NR3C1NPC1RAB9A | |
| SCHEMBL25593238 | 0.76 | ABL1 (0.47) | MAPTTRPV1AHRMEN1KMT2A | |
| SCHEMBL25590483 | 0.76 | EGFR (0.46) | MAPTTRPV1MEN1KMT2ANPC1 | |
| SCHEMBL25210996 | 0.75 | AHR (0.56) | MAPTTRPV1NR3C1AHRMEN1 | |
| SCHEMBL25590404 | 0.75 | AHR (0.45) | MAPTTRPV1NR3C1AHRMEN1 | |
| SCHEMBL25590564 | 0.74 | ROCK1 (0.48) | MAPTTRPV1AHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088435-A1 | PREPARATION FOR TRISUBSTITUTED PYRIDINE DERIVATIVE AND APPLICATION AS AROMATIC HYDROCARBON RECEPTOR MODULATOR | 成都奥睿药业有限公司 | 2023-05-25 | — | — | WO | disclosed |