Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GALR1 | P47211 | 2/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31655439 | 1.00 | TSHR (0.44) | TSHRLMNACYP2C9CYP2A6MAOA | |
| Methane SCHEMBL10428157 | 0.98 | TSHR (0.42) | TSHRLMNACYP2C9CYP2A6MAOA | |
| Cyclopropane SCHEMBL2363143 | 0.98 | TSHR (0.42) | TSHRLMNACYP2C9CYP2A6MAOA | |
| Cyclopropane SCHEMBL2363620 | 0.96 | TSHR (0.41) | TSHRLMNACYP2C9CYP2A6MAOA | |
| SCHEMBL407166 | 0.94 | TSHR (0.48) | TSHRLMNACYP2C9CYP2A6MAOA | |
| SCHEMBL61667 | 0.86 | CA1 (0.47) | TSHRCYP2A6CA2CA1CA9 | |
| SCHEMBL30533792 | 0.86 | CA1 (0.47) | TSHRCYP2A6CA2CA1CA9 | |
| Methoxymethane SCHEMBL10859333 | 0.79 | CA2 (0.42) | MAOAMAOBCA2CA1CA9 | |
| SCHEMBL3494049 | 0.74 | TSHR (0.50) | TSHRCYP2A6MAOAMAOBL3MBTL1 | |
| SCHEMBL6205306 | 0.74 | CYP2A6 (0.47) | LMNACYP2A6MAOAMAOBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 651 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072864-A | TDO2 INHIBITORS | 基因泰克公司 | 2019-07-30 | — | — | CN | claimed |
| US-7655686-B2 | Certain substituted spirocyclic lactams and use thereof as pharmaceuticals | NOVARTIS AG (CH) | 2010-02-02 | — | — | US | claimed |
| EP-1670803-B1 | CERTAIN SUBSTITUTED SPIROCYCLIC LACTAMS AND USE THEREOF AS PHARMACEUTICALS | NOVARTIS AG (CH) | 2008-03-12 | — | — | EP | claimed |
| EP-1874772-A1 | PURINE AND IMIDAZOPYRIDINE DERIVATIVES FOR IMMUNOSUPPRESSION | PHARMACOPEIA, INC. (US) | 2008-01-09 | — | — | EP | claimed |
| US-20070265328-A1 | Certain substituted spirocyclic lactams and use thereof as pharmaceuticals | NOVARTIS AG (CH) | 2007-11-15 | — | — | US | claimed |
| US-20070021443-A1 | Purine and imidazopyridine derivatives for immunosuppression | WYETH LLC | 2007-01-25 | — | — | US | claimed |
| US-20070015781-A1 | Certain substituted spirocyclic lactams and use thereof as pharmaceuticals | AUBERSON YVES | 2007-01-18 | — | — | US | claimed |
| WO-2006108103-A1 | PURINE AND IMIDAZOPYRIDINE DERIVATIVES FOR IMMUNOSUPPRESSION | PHARMACOPEIA, INC. (US) | 2006-10-12 | — | — | WO | claimed |
| EP-1670803-A1 | CERTAIN SUBSTITUTED SPIROCYCLIC LACTAMS AND USE THEREOF AS PHARMACEUTICALS | Novartis AG (CH) | 2006-06-21 | — | — | EP | claimed |
| WO-2005035535-A1 | CERTAIN SUBSTITUTED SPIROCYCLIC LACTAMS AND USE THEREOF AS PHARMACEUTICALS | NOVARTIS AG (CH) | 2005-04-21 | — | — | WO | claimed |
| US-20010014745-A1 | PROCESS FOR THE PREPARTION OF 6-(ARYLCARBONYL)-4-OXIMO-DIHYDROBENZOTHIOPYRAN HERBICIDES AND INTERMEDIATES USEFUL THEREIN | DOEHNER JR ROBERT FRANCIS (US) | 2001-08-16 | — | — | US | claimed |
| EP-0915092-B1 | Process for the preparation of 6-(arylcarbonyl)-4-oximo-dihydrobenzothiopyran herbicides and intermediates useful therein | BASF AG (DE) | 2001-06-13 | — | — | EP | claimed |
| US-6008402-A | REACTING CYCLOHEXADIENECARBOXYLATE-4-ONE COMPOUND WITH A BETA MERCAPTOPROPIONIC ACID TO GIVE THIOENOL, CYCLODEHYDRATING THE THIOENOL | AMERICAN CYANAMID COMPANY (US) | 1999-12-28 | — | — | US | claimed |
| EP-0915092-A1 | Process for the preparation of 6-(arylcarbonyl)-4-oximo-dihydrobenzothiopyran herbicides and intermediates useful therein | American Cyanamid Company (US) | 1999-05-12 | — | — | EP | claimed |
| JP-58194881-A | — | — | None | — | — | JP | disclosed |
| CN-120247868-A | Dihydrobenzothiopyran-1, 1-dioxide compounds, preparation method and application thereof | 中国人民解放军海军第九七一医院 | 2025-07-04 | — | — | CN | disclosed |
| US-20250019352-A1 | PHARMACOLOGICAL AGENTS FOR TREATING OPHTHALMIC DISEASES | PLEX PHARMACEUTICALS INC (US) | 2025-01-16 | — | — | US | disclosed |
| CN-1211976-A | Isoxazole derivatives and their use as herbicides | NOVARTIS AG (CH) | 1999-03-24 | — | — | CN | disclosed |
| US-5547980-A | ANTIALLERGENS, BRONCHODILATOR | BOEHRINGER MANNHEIM GMBH (DE) | 1996-08-20 | — | — | US | disclosed |
| JP-S58194881-A | IMPROVED METHOD FOR PREPARING 7-SULFONAMIDOTHIOCHROMAN-1,1-DIONE | HOKKO CHEM IND CO LTD | 1983-11-12 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265328-A1 | Certain substituted spirocyclic lactams and use thereof as pharmaceuticals | STS, RPS6KA5, RPIA | TSHR 1154/4885LMNA 2852/4885CYP2C9 272/4885 |
| US-20250019352-A1 | PHARMACOLOGICAL AGENTS FOR TREATING OPHTHALMIC DISEASES | CRYAB, CRYAA, CRYZ | TSHR 2774/4885LMNA 337/4885CYP2C9 4829/4885 |
| US-20070015781-A1 | Certain substituted spirocyclic lactams and use thereof as pharmaceuticals | STS, RPS6KA5, RPIA | TSHR 1154/4885LMNA 2852/4885CYP2C9 272/4885 |
| US-20070021443-A1 | Purine and imidazopyridine derivatives for immunosuppression | TPMT, P2RY4, P2RY1 | TSHR 3899/4885LMNA 4808/4885CYP2C9 1121/4885 |
| US-20010014745-A1 | PROCESS FOR THE PREPARTION OF 6-(ARYLCARBONYL)-4-OXIMO-DIHYDROBENZOTHIOPYRAN HERBICIDES AND INTERMEDIATES USEFUL THEREIN | DDT, CYP4X1, CYP2B6 | TSHR 1654/4885LMNA 2213/4885CYP2C9 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.