SCHEMBL25596309

SCHEMBL25596309

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc5c(-c6ccc(-c7ccc8c9c(cccc79)-c7ccccc7-8)cc6)cccc45)cc3)n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44
KEAP1 Q14145 1/20 0.44
NFE2L2 Q16236 1/20 0.44
L3MBTL1 Q9Y468 5/20 0.43
ALDH1A1 P00352 5/20 0.43
HPGD P15428 4/20 0.43
TSHR P16473 4/20 0.43
MAPK1 P28482 3/20 0.43
HSD17B10 Q99714 3/20 0.43
CASP1 P29466 1/20 0.43
HIF1A Q16665 1/20 0.43
MAPT P10636 4/20 0.42
ATM Q13315 3/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
KDM4E B2RXH2 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25596304 1.00 CRHBP (0.44) CRHBPCRHR2KEAP1NFE2L2L3MBTL1
SCHEMBL23546607 1.00 CRHBP (0.44) CRHBPCRHR2KEAP1NFE2L2L3MBTL1
SCHEMBL14079810 1.00 CRHBP (0.44) CRHBPCRHR2KEAP1NFE2L2L3MBTL1
SCHEMBL21309354 1.00 CRHBP (0.44) CRHBPCRHR2KEAP1NFE2L2L3MBTL1
SCHEMBL14079814 0.98 CRHBP (0.43) CRHBPCRHR2KEAP1NFE2L2L3MBTL1
SCHEMBL23099354 0.98 CRHBP (0.43) CRHBPCRHR2KEAP1NFE2L2L3MBTL1
SCHEMBL18878312 0.98 CRHBP (0.43) CRHBPCRHR2KEAP1NFE2L2L3MBTL1
SCHEMBL23099287 0.98 CRHBP (0.43) CRHBPCRHR2KEAP1NFE2L2L3MBTL1
SCHEMBL18878320 0.98 CRHBP (0.43) CRHBPCRHR2KEAP1NFE2L2L3MBTL1
SCHEMBL25823008 0.98 CRHBP (0.43) CRHBPCRHR2KEAP1NFE2L2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230165140-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2023-05-25 US disclosed
US-20230165140-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165140-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, TMEM109, TRPA1 CRHBP 4745/4885CRHR2 4341/4885KEAP1 695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.