Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TAF1 | P21675 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PTPRB | P23467 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25596762 | 0.79 | NR3C1 (0.42) | NR3C1PGRNR3C2ARBRD4 | |
| SCHEMBL30968937 | 0.79 | AHR (0.44) | NR3C1PGRNR3C2ARBRD4 | |
| SCHEMBL30456277 | 0.75 | KEAP1 (0.51) | NR3C1PGRNR3C2ARBRD4 | |
| SCHEMBL25596753 | 0.75 | NR3C1 (0.40) | NR3C1PGRNR3C2ARBRD4 | |
| SCHEMBL25363572 | 0.71 | NR3C1 (0.40) | NR3C1PGRNR3C2ARKEAP1 | |
| SCHEMBL31122401 | 0.71 | NR3C1 (0.40) | NR3C1PGRNR3C2ARKEAP1 | |
| SCHEMBL593678 | 0.67 | NR3C1 (0.62) | NR3C1PGRNR3C2ARBRD4 | |
| SCHEMBL1374474 | 0.66 | TNF (0.54) | NR3C1PGRNR3C2ARBRD4 | |
| SCHEMBL29591462 | 0.66 | TNF (0.54) | NR3C1PGRNR3C2ARBRD4 | |
| SCHEMBL10179358 | 0.63 | NR3C1 (0.41) | NR3C1PGRNR3C2ARBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484871-B1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2023-06-07 | — | — | EP | disclosed |