Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.33 |
| ▸ | FEN1 | P39748 | 3/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | TAF1 | P21675 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10180291 | 0.75 | P2RX7 (0.37) | NR3C1PGRNR3C2ARPTGS2 | |
| SCHEMBL10179553 | 0.72 | GPR84 (0.58) | ALOX5APFEN1GPR84CCR2AHR | |
| SCHEMBL8533144 | 0.72 | PTGS2 (0.43) | NR3C1PGRNR3C2ARPTGS2 | |
| SCHEMBL18876057 | 0.72 | TNF (0.38) | NR3C1PGRIKBKBCHUKTNF | |
| SCHEMBL2535930 | 0.71 | GPR84 (0.50) | ARIKBKBCHUKTNFRIPK1 | |
| SCHEMBL593678 | 0.69 | NR3C1 (0.62) | NR3C1PGRNR3C2ARACLY | |
| SCHEMBL10179175 | 0.68 | CSNK2A1 (0.41) | IKBKBCHUKTNFRIPK1GPR84 | |
| SCHEMBL1741436 | 0.68 | TNF (0.38) | IKBKBCHUKTNFRIPK1GPR84 | |
| SCHEMBL29991075 | 0.68 | TNF (0.47) | NR3C1PGRIKBKBCHUKTNF | |
| SCHEMBL1349668 | 0.67 | AHR (0.37) | NR3C1PGRNR3C2ARPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190192510-A1 | GPR119 AGONIST | NIPPON CHEMIPHAR CO., LTD. (JP) | 2019-06-27 | — | — | US | disclosed |
| EP-2532656-A1 | GPR119 AGONIST | Nippon Chemiphar Co., Ltd. (JP) | 2012-12-12 | — | — | EP | disclosed |
| US-20120245344-A1 | GPR119 AGONIST | NIPPON CHEMIPHAR CO., LTD. (JP) | 2012-09-27 | — | — | US | disclosed |
| EP-2474540-A1 | GPR119 AGONIST | Nippon Chemiphar Co., Ltd. (JP) | 2012-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190192510-A1 | GPR119 AGONIST | GPR119, GPR4, GPR27 | NR3C1 185/4885PGR 527/4885NR3C2 241/4885 |
| US-20120245344-A1 | GPR119 AGONIST | GPR119, GPR4, GPR55 | NR3C1 253/4885PGR 648/4885NR3C2 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.