SCHEMBL25599686

SCHEMBL25599686

CO/N=C(/C(=O)OC)c1cccc(C)c1CO/N=C(\CC(C)(F)F)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.43
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KCNK3 O14649 1/20 0.32
KCNK9 Q9NPC2 1/20 0.32
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
ERCC5 P28715 1/20 0.30
FEN1 P39748 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23972049 0.93 HIF1A (0.43) HIF1AKMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL25599741 0.93 HIF1A (0.44) HIF1AKMT2ASMN1; SMN2KCNK3KCNK9
SCHEMBL25599676 0.90 HIF1A (0.34) HIF1AKMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL23971918 0.86 HIF1A (0.44) HIF1AKMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL23971986 0.86 HIF1A (0.43) HIF1AKMT2ASMN1; SMN2KCNK3KCNK9
SCHEMBL23972034 0.85 SMN1; SMN2 (0.46) HIF1AKMT2ASMN1; SMN2PPARGPPARA
SCHEMBL25600178 0.84 HIF1A (0.43) HIF1AKMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL23971769 0.84 HIF1A (0.45) HIF1AKMT2AKCNK3KCNK9
SCHEMBL23971827 0.83 HIF1A (0.34) HIF1AKMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL25599750 0.83 HIF1A (0.34) HIF1AKMT2ASMN1; SMN2ERCC5FEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230172206-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS II BASF SE (DE) 2023-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172206-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS II COX5B, SQOR, UQCRB HIF1A 2078/4885KMT2A 3697/4885SMN1; SMN2 3370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.