SCHEMBL25599741

SCHEMBL25599741

CO/N=C(/C(=O)OC)c1cccc(C)c1CO/N=C(\CC(C)(F)F)c1ccccc1C

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.44
RXFP1 Q9HBX9 1/20 0.32
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ERCC5 P28715 1/20 0.31
FEN1 P39748 1/20 0.31
KCNK3 O14649 1/20 0.31
POLB P06746 1/20 0.31
KCNK9 Q9NPC2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25599686 0.93 HIF1A (0.43) HIF1AKMT2ASMN1; SMN2L3MBTL1ERCC5
SCHEMBL23971986 0.93 HIF1A (0.43) HIF1ARXFP1KMT2AMEN1ALDH1A1
SCHEMBL25599750 0.90 HIF1A (0.34) HIF1ARXFP1KMT2AMEN1ALDH1A1
SCHEMBL23972049 0.86 HIF1A (0.43) HIF1AKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL25599676 0.83 HIF1A (0.34) HIF1AKMT2ASMN1; SMN2KCNK3KCNK9
SCHEMBL23971982 0.83 HIF1A (0.34) HIF1ARXFP1KMT2AMEN1ALDH1A1
SCHEMBL23971794 0.82 HIF1A (0.43) HIF1AALDH1A1LMNAKCNK3KCNK9
SCHEMBL23972055 0.82 HIF1A (0.48) HIF1AKMT2AMEN1L3MBTL1ERCC5
SCHEMBL23971769 0.81 HIF1A (0.45) HIF1ARXFP1KMT2AMEN1ALDH1A1
SCHEMBL23979019 0.81 HIF1A (0.43) HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230172206-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS II BASF SE (DE) 2023-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172206-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS II COX5B, SQOR, UQCRB HIF1A 2078/4885RXFP1 4291/4885KMT2A 3697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.