Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17617087 | 1.00 | MAPT (0.31) | MAPTDPP4ALDH1A1PTGS1KMT2A | |
| SCHEMBL19009024 | 1.00 | MAPT (0.31) | MAPTDPP4ALDH1A1PTGS1KMT2A | |
| SCHEMBL8202933 | 0.83 | MAPT (0.34) | MAPTDPP4ALDH1A1PTGS1 | |
| SCHEMBL8426774 | 0.83 | MAPT (0.34) | MAPTDPP4ALDH1A1PTGS1 | |
| SCHEMBL12867478 | 0.83 | MAPT (0.34) | MAPTDPP4ALDH1A1PTGS1 | |
| Hydrochloric Acid SCHEMBL1174259 | 0.81 | DPP4 (0.33) | MAPTDPP4ALDH1A1PTGS1 | |
| SCHEMBL1174655 | 0.77 | DPP4 (0.50) | MAPTDPP4ALDH1A1PTGS1 | |
| SCHEMBL342534 | 0.77 | DPP4 (0.50) | MAPTDPP4ALDH1A1PTGS1 | |
| SCHEMBL343358 | 0.77 | DPP4 (0.50) | MAPTDPP4ALDH1A1PTGS1 | |
| SCHEMBL3171063 | 0.77 | CA2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4198031-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | Merck Patent GmbH (DE) | 2023-06-21 | — | — | EP | disclosed |