Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CIT | O14578 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 10/20 | 0.33 |
| ▸ | MMP3 | P08254 | 9/20 | 0.33 |
| ▸ | MMP2 | P08253 | 8/20 | 0.33 |
| ▸ | MMP9 | P14780 | 7/20 | 0.33 |
| ▸ | MMP8 | P22894 | 4/20 | 0.33 |
| ▸ | MMP13 | P45452 | 3/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.32 |
| ▸ | MMP7 | P09237 | 2/20 | 0.32 |
| ▸ | MMP14 | P50281 | 2/20 | 0.32 |
| ▸ | TNF | P01375 | 2/20 | 0.32 |
| ▸ | MMP20 | O60882 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | MMP10 | P09238 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP15 | P51511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1174655 | 1.00 | DPP4 (0.50) | DPP4ALDH1A1MAPTPTGS1CIT | |
| SCHEMBL343358 | 1.00 | DPP4 (0.50) | DPP4ALDH1A1MAPTPTGS1CIT | |
| Hydrochloric Acid SCHEMBL2005453 | 0.97 | DPP4 (0.48) | DPP4ALDH1A1MAPTPTGS1CIT | |
| Hydrochloric Acid SCHEMBL20721188 | 0.97 | DPP4 (0.48) | DPP4ALDH1A1MAPTPTGS1CIT | |
| Hydrochloric Acid SCHEMBL2005458 | 0.97 | DPP4 (0.48) | DPP4ALDH1A1MAPTPTGS1CIT | |
| Trifluoroacetic Acid SCHEMBL7399856 | 0.87 | DPP4 (0.42) | DPP4ALDH1A1MAPTPTGS1CIT | |
| SCHEMBL3416457 | 0.82 | SPHK1 (0.41) | DPP4ALDH1A1MAPTPTGS1 | |
| SCHEMBL12867478 | 0.80 | MAPT (0.34) | DPP4ALDH1A1MAPTPTGS1FAP | |
| SCHEMBL14261061 | 0.80 | DPP4 (0.47) | DPP4ALDH1A1MAPTPTGS1CIT | |
| SCHEMBL8202933 | 0.80 | MAPT (0.34) | DPP4ALDH1A1MAPTPTGS1FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250214928-A1 | Process for the preparation of marimastat, marimastat prepared by this process, a pharmaceutical composition comprising the same, and uses thereof | PIKRALIDA SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) | 2025-07-03 | — | — | US | claimed |
| US-20230364272-A1 | THERANOSTIC COMPOUNDS | UNIVERSITY OF CAPE TOWN (ZA) | 2023-11-16 | — | — | US | claimed |
| US-20230033510-A1 | Compounds and Methods for Treatment of Visceral Pain | ARENA PHARMACEUTICALS, INC. | 2023-02-02 | — | — | US | claimed |
| US-20210060040-A1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. | 2021-03-04 | — | — | US | claimed |
| US-10632134-B2 | Cannabinoid receptor modulators | ARENA PHARMACEUTICALS, INC. (US) | 2020-04-28 | — | — | US | claimed |
| US-20200078358-A1 | Compounds and Methods for Treatment of Visceral Pain | ARENA PHARMACEUTICALS, INC. | 2020-03-12 | — | — | US | claimed |
| CN-110709085-A | Compounds and methods for treating visceral pain | 艾尼纳制药公司 | 2020-01-17 | — | — | CN | claimed |
| CN-109970708-A | Cannibinoid receptor modulators | 艾尼纳制药公司 | 2019-07-05 | — | — | CN | claimed |
| CN-103492369-B | Cannabinoid receptor modulators | 艾尼纳制药公司 | 2019-03-29 | — | — | CN | claimed |
| US-20180354907-A1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. | 2018-12-13 | — | — | US | claimed |
| US-20120316147-A1 | NOVEL PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-12-13 | — | — | US | claimed |
| WO-2012168350-A1 | PYRIDIN- 2 -AMIDES USEFUL AS CB2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-12-13 | — | — | WO | claimed |
| US-20120214766-A1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. | 2012-08-23 | — | — | US | claimed |
| US-20090220514-A1 | ADAM10 and its Uses Related to Infection | VANDERBILT UNIVERSITY | 2009-09-03 | — | — | US | claimed |
| EP-1224211-B1 | PROCESS FOR THE PREPARATION OF A DIPEPTIDE AND INTERMEDIATE PRODUCT IN SUCH A PROCESS | DSM NV (NL) | 2003-04-16 | — | — | EP | claimed |
| US-6486193-B2 | ANTIARTHRITIC AGENTS; ANTIINFLAMMATORY AGENTS | AVENTIS PHARMACEUTICALS INC. | 2002-11-26 | — | — | US | claimed |
| EP-1224211-A1 | PROCESS FOR THE PREPARATION OF A DIPEPTIDE AND INTERMEDIATE PRODUCT IN SUCH A PROCESS | DSM N.V. (NL) | 2002-07-24 | — | — | EP | claimed |
| US-20020037859-A1 | 3-substituted pyrrolidines useful as inhibitors of matrix metalloproteinases | AVENTISUB INC. | 2002-03-28 | — | — | US | claimed |
| EP-0818443-B1 | Mercaptoketones and mercaptoalcohols, a process for their preparation and their use as inhibitors of matrix metalloproteinases | AMERICAN CYANAMID CO (US) | 2001-12-05 | — | — | EP | claimed |
| WO-2001030807-A1 | PROCESS FOR THE PREPARATION OF A DIPEPTIDE AND INTERMEDIATE PRODUCT IN SUCH A PROCESS | DSM N.V. (NL) | 2001-05-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214766-A1 | CANNABINOID RECEPTOR MODULATORS | CNR1, CNR2, TRPV1 | DPP4 4074/4885ALDH1A1 3623/4885MAPT 627/4885 |
| US-20200078358-A1 | Compounds and Methods for Treatment of Visceral Pain | VIP, FABP2, FABP6 | DPP4 1022/4885ALDH1A1 603/4885MAPT 3544/4885 |
| US-20180354907-A1 | CANNABINOID RECEPTOR MODULATORS | CNR1, CNR2, TRPV1 | DPP4 4074/4885ALDH1A1 3623/4885MAPT 627/4885 |
| US-10632134-B2 | Cannabinoid receptor modulators | CNR1, CNR2, GPR18 | DPP4 4760/4885ALDH1A1 2571/4885MAPT 3883/4885 |
| US-20230364272-A1 | THERANOSTIC COMPOUNDS | MMP12, TIMP3, CTSZ | DPP4 344/4885ALDH1A1 1414/4885MAPT 689/4885 |
| US-20210060040-A1 | CANNABINOID RECEPTOR MODULATORS | CNR1, CNR2, GPR18 | DPP4 4760/4885ALDH1A1 2571/4885MAPT 3883/4885 |
| US-20120316147-A1 | NOVEL PYRIDINE DERIVATIVES | NDUFS6, NDUFS4, NDUFV1 | DPP4 2226/4885ALDH1A1 269/4885MAPT 1821/4885 |
| US-20090220514-A1 | ADAM10 and its Uses Related to Infection | ADAM10, ADAM12, ADAM17 | DPP4 232/4885ALDH1A1 4310/4885MAPT 3451/4885 |
| US-20250214928-A1 | Process for the preparation of marimastat, marimastat prepared by this process, a pharmaceutical composition comprising the same, and uses thereof | MMP7, MMP9, MMP3 | DPP4 463/4885ALDH1A1 1330/4885MAPT 407/4885 |
| US-20230033510-A1 | Compounds and Methods for Treatment of Visceral Pain | VIP, FABP2, FABP6 | DPP4 1022/4885ALDH1A1 603/4885MAPT 3544/4885 |
| US-20020037859-A1 | 3-substituted pyrrolidines useful as inhibitors of matrix metalloproteinases | MMP3, MMP1, MMP9 | DPP4 329/4885ALDH1A1 281/4885MAPT 3351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.