Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CIT | O14578 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 10/20 | 0.33 |
| ▸ | MMP3 | P08254 | 9/20 | 0.33 |
| ▸ | MMP2 | P08253 | 8/20 | 0.33 |
| ▸ | MMP9 | P14780 | 7/20 | 0.33 |
| ▸ | MMP8 | P22894 | 4/20 | 0.33 |
| ▸ | MMP13 | P45452 | 3/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.32 |
| ▸ | MMP7 | P09237 | 2/20 | 0.32 |
| ▸ | MMP14 | P50281 | 2/20 | 0.32 |
| ▸ | TNF | P01375 | 2/20 | 0.32 |
| ▸ | MMP20 | O60882 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | MMP10 | P09238 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP15 | P51511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1174655 | 1.00 | DPP4 (0.50) | DPP4ALDH1A1MAPTPTGS1CIT | |
| SCHEMBL342534 | 1.00 | DPP4 (0.50) | DPP4ALDH1A1MAPTPTGS1CIT | |
| Hydrochloric Acid SCHEMBL2005453 | 0.97 | DPP4 (0.48) | DPP4ALDH1A1MAPTPTGS1CIT | |
| Hydrochloric Acid SCHEMBL20721188 | 0.97 | DPP4 (0.48) | DPP4ALDH1A1MAPTPTGS1CIT | |
| Hydrochloric Acid SCHEMBL2005458 | 0.97 | DPP4 (0.48) | DPP4ALDH1A1MAPTPTGS1CIT | |
| Trifluoroacetic Acid SCHEMBL7399856 | 0.87 | DPP4 (0.42) | DPP4ALDH1A1MAPTPTGS1CIT | |
| SCHEMBL3416457 | 0.82 | SPHK1 (0.41) | DPP4ALDH1A1MAPTPTGS1 | |
| SCHEMBL12867478 | 0.80 | MAPT (0.34) | DPP4ALDH1A1MAPTPTGS1FAP | |
| SCHEMBL14261061 | 0.80 | DPP4 (0.47) | DPP4ALDH1A1MAPTPTGS1CIT | |
| SCHEMBL8202933 | 0.80 | MAPT (0.34) | DPP4ALDH1A1MAPTPTGS1FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250214928-A1 | Process for the preparation of marimastat, marimastat prepared by this process, a pharmaceutical composition comprising the same, and uses thereof | PIKRALIDA SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) | 2025-07-03 | — | — | US | claimed |
| EP-3385252-B1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARM INC (US) | 2022-09-21 | — | — | EP | claimed |
| EP-1532132-B1 | NOVEL BENZODIOXOLES | HOFFMANN LA ROCHE (CH) | 2008-03-19 | — | — | EP | claimed |
| US-20050143373-A1 | Benzodioxole derivatives | ALANINE ALEXANDER (FR) | 2005-06-30 | — | — | US | claimed |
| US-20040142922-A1 | Benzodioxole derivatives | HOFFMANN-LA ROCHE INC. | 2004-07-22 | — | — | US | claimed |
| US-20250214928-A1 | Process for the preparation of marimastat, marimastat prepared by this process, a pharmaceutical composition comprising the same, and uses thereof | PIKRALIDA SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) | 2025-07-03 | — | — | US | disclosed |
| US-12109219-B2 | Cannabinoid receptor modulators | ARENA PHARMACEUTICALS, INC. (US) | 2024-10-08 | — | — | US | disclosed |
| US-11771695-B2 | Cannabinoid receptor modulators | ARENA PHARMACEUTICALS, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-11746091-B2 | Cannabinoid receptor modulators | ARENA PHARMACEUTICALS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| US-20220402866-A1 | 3,4-DISUBSTITUTED 3-CYCLOBUTENE-1,2-DIONES AND USE THEREOF | ALLERGAN, INC. | 2022-12-22 | — | — | US | disclosed |
| US-20220306586-A1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. | 2022-09-29 | — | — | US | disclosed |
| EP-3385252-B1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARM INC (US) | 2022-09-21 | — | — | EP | disclosed |
| WO-1998003516-A1 | PHOSPHINATE BASED INHIBITORS OF MATRIX METALLOPROTEASES | PFIZER INC. (US) | 1998-01-29 | — | — | WO | disclosed |
| EP-0763012-A1 | SUCCINYL HYDROXAMIC ACID, N-FORMYL-N-HYDROXY AMINO CARBOXYLIC ACID AND SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| EP-0749302-A1 | HYDROXAMIC ACID AND CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | SANOFI WINTHROP, INC. (US) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995032944-A1 | SUCCINYL HYDROXAMIC ACID, N-FORMYL-N-HYDROXY AMINO CARBOXYLIC ACID AND SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-12-07 | — | — | WO | disclosed |
| WO-1995022966-A1 | HYDROXAMIC ACID AND CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | SANOFI WINTHROP, INC. (US) | 1995-08-31 | — | — | WO | disclosed |
| WO-1995004033-A1 | SUCCINAMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS GELATINASE AND COLLAGENASE INHIBITORS | CELLTECH LIMITED (GB) | 1995-02-09 | — | — | WO | disclosed |
| US-5304549-A | Control or prevention of degenerative joint diseases | HOFFMANN-LA ROCHE INC. (US) | 1994-04-19 | — | — | US | disclosed |
| EP-0497192-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143373-A1 | Benzodioxole derivatives | CNR2, CNR1, GPR119 | DPP4 1903/4885ALDH1A1 607/4885MAPT 4230/4885 |
| US-20220306586-A1 | CANNABINOID RECEPTOR MODULATORS | CNR1, CNR2, TRPV1 | DPP4 4074/4885ALDH1A1 3623/4885MAPT 627/4885 |
| US-20040142922-A1 | Benzodioxole derivatives | CNR1, CNR2, GPR119 | DPP4 2221/4885ALDH1A1 299/4885MAPT 4527/4885 |
| US-20220402866-A1 | 3,4-DISUBSTITUTED 3-CYCLOBUTENE-1,2-DIONES AND USE THEREOF | IL17A, TSLP, SSB | DPP4 455/4885ALDH1A1 365/4885MAPT 3678/4885 |
| US-11746091-B2 | Cannabinoid receptor modulators | CNR1, CNR2, TRPV1 | DPP4 4074/4885ALDH1A1 3623/4885MAPT 627/4885 |
| US-20250214928-A1 | Process for the preparation of marimastat, marimastat prepared by this process, a pharmaceutical composition comprising the same, and uses thereof | MMP7, MMP9, MMP3 | DPP4 463/4885ALDH1A1 1330/4885MAPT 407/4885 |
| US-11771695-B2 | Cannabinoid receptor modulators | CNR2, CNR1, OPRL1 | DPP4 4488/4885ALDH1A1 2692/4885MAPT 3271/4885 |
| US-12109219-B2 | Cannabinoid receptor modulators | CNR1, CNR2, GPR18 | DPP4 4760/4885ALDH1A1 2571/4885MAPT 3883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.