Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 10/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 5/20 | 0.42 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 9/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31282296 | 1.00 | TRAP1 (0.42) | TRAP1HSP90B1SPRHSP90AA1HSP90AB1 | |
| SCHEMBL31281835 | 0.89 | TRAP1 (0.45) | TRAP1HSP90B1SPRHSP90AA1HSP90AB1 | |
| SCHEMBL31282001 | 0.85 | TRAP1 (0.36) | TRAP1HSP90B1SPRHSP90AA1HSP90AB1 | |
| SCHEMBL25599247 | 0.85 | HSP90AA1 (0.40) | TRAP1HSP90B1SPRHSP90AA1HSP90AB1 | |
| SCHEMBL25221414 | 0.85 | TRAP1 (0.43) | TRAP1HSP90B1SPRHSP90AA1HSP90AB1 | |
| SCHEMBL30377827 | 0.85 | TRAP1 (0.43) | TRAP1HSP90B1SPRHSP90AA1HSP90AB1 | |
| SCHEMBL31281765 | 0.83 | TRAP1 (0.35) | TRAP1HSP90B1SPRHSP90AA1HSP90AB1 | |
| SCHEMBL25599287 | 0.83 | TRAP1 (0.35) | TRAP1HSP90B1SPRHSP90AA1HSP90AB1 | |
| SCHEMBL31335642 | 0.83 | SPR (0.44) | TRAP1HSP90B1SPRHSP90AA1HSP90AB1 | |
| SCHEMBL25601416 | 0.82 | TRAP1 (0.38) | TRAP1HSP90B1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094834-A1 | ISOINDOLINES AS PMS2 INHIBITORS | Neophore Limited (GB) | 2023-06-01 | — | — | WO | disclosed |