Phenylguanidine

Phenylguanidine

SCHEMBL256023

N=C(N)Nc1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.58
▸ TAS2R38 P59533 3/20 0.58
▸ HSD17B10 Q99714 3/20 0.58
▸ TP53 P04637 2/20 0.58
▸ TSHR P16473 2/20 0.58
▸ TYR P14679 1/20 0.58
▸ GAA P10253 4/20 0.50
▸ KMT2A Q03164 3/20 0.50
▸ MAPT P10636 2/20 0.50
▸ LMNA P02545 2/20 0.50
▸ CYP2D6 P10635 2/20 0.50
▸ TDP1 Q9NUW8 2/20 0.50
▸ CYP3A4 P08684 2/20 0.50
▸ GFER P55789 1/20 0.50
▸ EPHX1 P07099 1/20 0.50
▸ EPHX2 P34913 1/20 0.50
▸ CDK9 P50750 1/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ CLK4 Q9HAZ1 1/20 0.50
▸ GRIN2D O15399 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylguanidine SCHEMBL11092906 0.97 ALDH1A1 (0.56) ALDH1A1TAS2R38HSD17B10TP53TSHR
Phenylguanidine SCHEMBL29249611 0.97 ALDH1A1 (0.56) ALDH1A1TAS2R38HSD17B10TP53TSHR
Phenylguanidine SCHEMBL4027020 0.97 ALDH1A1 (0.56) ALDH1A1TAS2R38HSD17B10TP53TSHR
Phenylguanidine SCHEMBL28414520 0.93 HSD17B10 (0.52) ALDH1A1TAS2R38HSD17B10TP53TSHR
Phenylguanidine SCHEMBL1950328 0.93 TP53 (0.56) ALDH1A1TAS2R38HSD17B10TP53TSHR
Phenylguanidine SCHEMBL300643 0.93 TP53 (0.56) ALDH1A1TAS2R38HSD17B10TP53TSHR
SCHEMBL13062975 0.91 MAPT (0.64) ALDH1A1TAS2R38HSD17B10TP53TSHR
Phenylguanidine SCHEMBL8887604 0.91 TP53 (0.54) ALDH1A1TAS2R38HSD17B10TP53TSHR
Phenylguanidine SCHEMBL28765733 0.89 HSD17B10 (0.48) ALDH1A1TAS2R38HSD17B10TP53TSHR
Phenylguanidine SCHEMBL11154590 0.89 HSD17B10 (0.59) ALDH1A1TAS2R38HSD17B10TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2554 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12447645-B2 Modified timber GEORG-AUGUST-UNIVERSITAT GOTTINGEN STIFTUNG OFFENTLICHEN RECHTS (DE) 2025-10-21 — — US claimed
CN-120022762-A Nanofiltration composite membrane and preparation method and application thereof 中国科学院大连化学物理研究所 2025-05-23 — — CN claimed
CN-117865165-B Preparation method and application of ultra-small particle and high-stability silicon dioxide colloid 山东科翰硅源新材料有限公司 2024-09-17 — — CN claimed
EP-4031338-B1 MODIFIED TIMBER GEORG AUGUST UNIV GOETTINGEN (DE) 2024-07-31 — — EP claimed
CN-118104663-A Synergistic compound composition containing nicotine pesticide and application thereof 沈阳中化农药化工研发有限公司 2024-05-31 — — CN claimed
CN-115096872-B Method for detecting copper ions by using silent region SERS probe and application thereof 暨南大学 2024-05-31 — — CN claimed
CN-117865165-A Preparation method and application of ultra-small particle and high-stability silicon dioxide colloid 山东科翰硅源新材料有限公司 2024-04-12 — — CN claimed
CN-117539135-A Corrosion-free photoresist stripper 南通群安电子材料有限公司 2024-02-09 — — CN claimed
CN-116510525-B High-flux nanofiltration membrane based on guanidino compound and preparation method and application thereof 天津大学 2023-09-01 — — CN claimed
CN-116510525-A High-flux nanofiltration membrane based on guanidino compound and preparation method and application thereof 天津大学 2023-08-01 — — CN claimed
WO-1984004455-A1 POTENTIATION OF ANTHELMINTICS COMMW SCIENT IND RES ORG (AU) 1984-11-22 — — WO claimed
EP-0018134-B1 DIHYDROPYRIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BEECHAM GROUP PLC (GB) 1984-03-14 — — EP claimed
EP-0098034-A2 A process for producing n-phosphonomethylglycine derivatives and herbicidal compounds and compositions prepared thereby Geshuri Laboratories Ltd. (IL) 1984-01-11 — — EP claimed
US-4404219-A ORAL HYPOGLYCEMIC AGENTS; DIABETES PFIZER INC. (US) 1983-09-13 — — US claimed
US-4293690-A PROTECTING HYDROXYLS OF 5-AMINO-1-B-D-RIBOFURANOSYLIMIDAZOLE-4-CARBOXAMIDE, DEHYDRATION, CYCLIZATION TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1981-10-06 — — US claimed
US-4281004-A FOR TREATMENT OF DIABETES PFIZER INC. (US) 1981-07-28 — — US claimed
EP-0017465-A1 Production of 2,6-diaminonebularines Takeda Chemical Industries, Ltd. (JP) 1980-10-15 — — EP claimed
US-4176192-A ANTHELMINTICS HOECHST AKTIENGESELLSCHAFT (DE) 1979-11-27 — — US claimed
US-4113282-A TETRANITRODIPHENYL ACETIC ACID DERIVATIVES THE MEAD CORPORATION (US) 1978-09-12 — — US claimed
US-3976787-A VASOCONSTRICTION ARMOUR PHARMACEUTICAL COMPANY (US) 1976-08-24 — — US claimed
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