Phenylguanidine

Phenylguanidine

SCHEMBL28414520

C=O.N=C(N)Nc1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.52
ALDH1A1 P00352 3/20 0.52
TP53 P04637 2/20 0.52
TSHR P16473 2/20 0.52
TAS2R38 P59533 2/20 0.52
TYR P14679 1/20 0.52
GAA P10253 2/20 0.50
MAPT P10636 1/20 0.50
GFER P55789 1/20 0.50
EPHX1 P07099 1/20 0.50
EPHX2 P34913 1/20 0.50
CDK9 P50750 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CLK4 Q9HAZ1 1/20 0.50
TGM2 P21980 2/20 0.47
NAPRT Q6XQN6 1/20 0.46
PLAU P00749 2/20 0.46
F2 P00734 1/20 0.46
PLG P00747 1/20 0.46
PLAT P00750 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylguanidine SCHEMBL256023 0.93 ALDH1A1 (0.58) HSD17B10ALDH1A1TP53TSHRTAS2R38
Phenylguanidine SCHEMBL300643 0.91 TP53 (0.56) HSD17B10ALDH1A1TP53TSHRTAS2R38
Phenylguanidine SCHEMBL1950328 0.91 TP53 (0.56) HSD17B10ALDH1A1TP53TSHRTAS2R38
Phenylguanidine SCHEMBL11092906 0.91 ALDH1A1 (0.56) HSD17B10ALDH1A1TP53TSHRTAS2R38
Phenylguanidine SCHEMBL4027020 0.91 ALDH1A1 (0.56) HSD17B10ALDH1A1TP53TSHRTAS2R38
Phenylguanidine SCHEMBL29249611 0.91 ALDH1A1 (0.56) HSD17B10ALDH1A1TP53TSHRTAS2R38
Phenylguanidine SCHEMBL8887604 0.89 TP53 (0.54) HSD17B10ALDH1A1TP53TSHRTAS2R38
Phenylguanidine SCHEMBL28765733 0.87 HSD17B10 (0.48) HSD17B10ALDH1A1TP53TSHRTAS2R38
Phenylguanidine SCHEMBL11154590 0.87 HSD17B10 (0.59) HSD17B10ALDH1A1TP53TSHRTAS2R38
SCHEMBL13062975 0.84 MAPT (0.64) HSD17B10ALDH1A1TP53TSHRTAS2R38

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111295344-B Aluminum container containing a dicarbonate 朗盛德国有限责任公司 2022-07-15 CN disclosed
CN-111356595-A Coating tool 派通株式会社 2020-06-30 CN disclosed
CN-111295344-A Aluminum container containing a dicarbonate 朗盛德国有限责任公司 2020-06-16 CN disclosed