⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2558245 | 0.86 | CYP11B2 (0.32) | — | |
| SCHEMBL2556274 | 0.84 | CYP11B2 (0.32) | — | |
| SCHEMBL2563159 | 0.83 | OPRK1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL2559362 | 0.82 | OPRK1 (0.37) | — | |
| SCHEMBL2559627 | 0.82 | CCNT1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL2556061 | 0.82 | CCNT1 (0.38) | — | |
| SCHEMBL2557694 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL2561790 | 0.81 | CYP11B2 (0.32) | — | |
| SCHEMBL2559625 | 0.81 | CYP11B2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL2559948 | 0.80 | APP (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558467-A1 | ARYL - /HETEROARYL - CYCLOHEXENYL - TETRAAZABENZO [E]AZULENES AS VASOPRESSIN ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011128265-A1 | ARYL - /HETEROARYL - CYCLOHEXENYL - TETRAAZABENZO [E] AZULENES AS VASOPRESSIN ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-10-20 | — | — | WO | disclosed |