Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL256088 | 0.99 | L3MBTL1 (0.60) | L3MBTL1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL257067 | 0.89 | SMN1; SMN2 (0.64) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16638506 | 0.85 | L3MBTL1 (0.59) | L3MBTL1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL16638507 | 0.84 | L3MBTL1 (0.57) | L3MBTL1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL30088674 | 0.82 | L3MBTL1 (0.55) | L3MBTL1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL257065 | 0.81 | TDP1 (0.60) | NPC1KMT2AALDH1A1MEN1POLB | |
| SCHEMBL10777343 | 0.80 | TDP1 (0.55) | NPC1RAB9AKMT2ASMN1; SMN2MAPT | |
| SCHEMBL5953095 | 0.79 | TDP1 (0.70) | RAB9AKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL13612755 | 0.76 | RAB9A (0.72) | L3MBTL1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11439258 | 0.75 | TDP1 (0.47) | NPC1RAB9AKMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012028578-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |