Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL256091 | 0.89 | L3MBTL1 (0.61) | SMN1; SMN2RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL256088 | 0.88 | L3MBTL1 (0.60) | SMN1; SMN2RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL9967740 | 0.86 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9AALDH1A1BLMMEN1 | |
| SCHEMBL256087 | 0.83 | MEN1 (0.59) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL10777343 | 0.77 | TDP1 (0.55) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL5953095 | 0.76 | TDP1 (0.70) | RAB9AALDH1A1MEN1KMT2AGAA | |
| SCHEMBL16638506 | 0.74 | L3MBTL1 (0.59) | SMN1; SMN2RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL3687471 | 0.74 | KDM4E (0.50) | SMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL257065 | 0.73 | TDP1 (0.60) | ALDH1A1MEN1KMT2ANPC1KDM4E | |
| SCHEMBL16638507 | 0.73 | L3MBTL1 (0.57) | SMN1; SMN2RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012028578-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |