Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TERT | O14746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL256087 | 0.88 | MEN1 (0.59) | POLBALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL9967741 | 0.86 | TDP1 (0.58) | TDP1POLBALDH1A1KDM4EHPGD | |
| SCHEMBL256088 | 0.82 | L3MBTL1 (0.60) | TDP1POLBALDH1A1KDM4EHPGD | |
| SCHEMBL256091 | 0.81 | L3MBTL1 (0.61) | TDP1POLBALDH1A1MEN1KMT2A | |
| SCHEMBL10777343 | 0.77 | TDP1 (0.55) | TDP1POLBMEN1KMT2ALMNA | |
| SCHEMBL8251278 | 0.76 | REV1 (0.67) | TDP1POLBALDH1A1KDM4EHPGD | |
| SCHEMBL5953095 | 0.76 | TDP1 (0.70) | TDP1ALDH1A1KDM4EMEN1KMT2A | |
| Ethyl Piperidinoacetylaminobenzoate SCHEMBL31036207 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL13185628 | 0.74 | REV1 (0.69) | TDP1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL16638505 | 0.74 | ALDH1A1 (0.55) | POLBALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012028578-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |