Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25611033 | 0.97 | USP30 (0.48) | USP30NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL25611109 | 0.90 | USP30 (0.47) | USP30EGLN2XDH | |
| SCHEMBL25610836 | 0.88 | ALDH1A1 (0.48) | USP30NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL25610969 | 0.87 | USP30 (0.45) | USP30EGLN2XDH | |
| SCHEMBL25610970 | 0.87 | USP30 (0.45) | USP30EGLN2XDH | |
| SCHEMBL25611032 | 0.86 | USP30 (0.43) | USP30XDH | |
| SCHEMBL25611227 | 0.82 | UCHL1 (0.41) | USP30XDH | |
| SCHEMBL25605336 | 0.82 | MKNK1 (0.59) | USP30XDH | |
| SCHEMBL25611030 | 0.82 | XDH (0.38) | USP30XDH | |
| SCHEMBL25613444 | 0.80 | XDH (0.43) | USP30XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107714-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |