Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2553897 | 0.83 | MEN1 (0.58) | MEN1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL14553212 | 0.81 | MEN1 (0.52) | MEN1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL12264900 | 0.78 | MEN1 (0.66) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL2557760 | 0.77 | MEN1 (0.48) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL2557260 | 0.77 | KDM4E (0.48) | MEN1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL2557580 | 0.77 | KMT2A (0.48) | MEN1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL2560863 | 0.75 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL2576433 | 0.74 | TSHR (0.47) | MEN1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL16500084 | 0.73 | TSHR (0.43) | MEN1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL16500135 | 0.72 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552895-B1 | PYRAZOLE SYNTHESIS BY COUPLING OF CARBOXYLIC ACID DERIVATIVES AND ENAMINES | Westfälische Wilhelms Universität Münster (DE) | 2015-02-25 | — | — | EP | disclosed |
| EP-2552895-A1 | PYRAZOLE SYNTHESIS BY COUPLING OF CARBOXYLIC ACID DERIVATIVES AND ENAMINES | Westfälische Wilhelms-Universität Münster (DE) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011120861-A1 | PYRAZOLE SYNTHESIS BY COUPLING OF CARBOXYLIC ACID DERIVATIVES AND ENAMINES | WESTFÄLISHE WILHELMS-UNIVERSITÄT MÜNSTER (DE) | 2011-10-06 | — | — | WO | disclosed |