Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2553897 | 0.90 | MEN1 (0.58) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL2560863 | 0.82 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL2557760 | 0.81 | MEN1 (0.48) | KMT2AMEN1TP53ALDH1A1MAPT | |
| SCHEMBL12264903 | 0.81 | KMT2A (0.62) | KMT2AMEN1TP53ALDH1A1MAPT | |
| SCHEMBL16500135 | 0.79 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL2554340 | 0.78 | KMT2A (0.56) | KMT2AMEN1TP53ALDH1A1MAPT | |
| SCHEMBL14482132 | 0.78 | KMT2A (0.79) | KMT2AMEN1TP53ALDH1A1MAPT | |
| SCHEMBL2561201 | 0.77 | MEN1 (0.42) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL2557260 | 0.77 | KDM4E (0.48) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL16500067 | 0.75 | TP53 (0.48) | KMT2AMEN1TP53ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552895-B1 | PYRAZOLE SYNTHESIS BY COUPLING OF CARBOXYLIC ACID DERIVATIVES AND ENAMINES | Westfälische Wilhelms Universität Münster (DE) | 2015-02-25 | — | — | EP | disclosed |
| EP-2552895-A1 | PYRAZOLE SYNTHESIS BY COUPLING OF CARBOXYLIC ACID DERIVATIVES AND ENAMINES | Westfälische Wilhelms-Universität Münster (DE) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011120861-A1 | PYRAZOLE SYNTHESIS BY COUPLING OF CARBOXYLIC ACID DERIVATIVES AND ENAMINES | WESTFÄLISHE WILHELMS-UNIVERSITÄT MÜNSTER (DE) | 2011-10-06 | — | — | WO | disclosed |