Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRND | Q07001 | 1/20 | 0.33 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25614994 | 0.81 | CA12 (0.39) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL25614993 | 0.77 | CA12 (0.45) | CA12CA1CA2CA9CHRNB4 | |
| SCHEMBL25614742 | 0.76 | CHRNB4 (0.39) | CA12CA1CA2CA9CHRNB4 | |
| SCHEMBL14955293 | 0.74 | CA12 (0.51) | CA12CA1CA2CA9CYP2A6 | |
| SCHEMBL30811674 | 0.72 | KDM4E (0.44) | CHRNB4CHRNA3CHRNB2CHRNA4CYP2A6 | |
| SCHEMBL25614588 | 0.72 | KDM4E (0.44) | CHRNB4CHRNA3CHRNB2CHRNA4CYP2A6 | |
| SCHEMBL25614467 | 0.71 | CHRNA3 (0.44) | CHRNB4CHRNA3CHRNB2CHRNA4CYP2A6 | |
| SCHEMBL15105004 | 0.70 | CA12 (0.59) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL3043828 | 0.68 | CA12 (0.61) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL25614130 | 0.67 | CHRNB2 (0.48) | CHRNB4CHRNA3CHRNB2CHRNA4CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104209-A1 | METTL3 INHIBITOR COMPOUND | 上海昂阔医药有限公司 | 2023-06-15 | — | — | WO | disclosed |