Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25614983 | 0.81 | CA12 (0.42) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL25614740 | 0.78 | GABRA1 (0.37) | CA12CA1CA2CA9GABRA1 | |
| SCHEMBL25614598 | 0.75 | KDM4E (0.40) | GRM5 | |
| SCHEMBL25614466 | 0.74 | GRM5 (0.31) | GRM5 | |
| SCHEMBL25614993 | 0.73 | CA12 (0.45) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL30811694 | 0.71 | GRM5 (0.31) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL14955293 | 0.70 | CA12 (0.51) | CA12CA1CA2CA9CYP3A4 | |
| SCHEMBL30811822 | 0.70 | CHRNB2 (0.37) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL22531723 | 0.69 | GRM5 (0.38) | GRM5 | |
| SCHEMBL29176201 | 0.68 | CYP1A2 (0.30) | CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104209-A1 | METTL3 INHIBITOR COMPOUND | 上海昂阔医药有限公司 | 2023-06-15 | — | — | WO | disclosed |