Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF1 | Q13422 | 3/20 | 0.37 |
| ▸ | IKZF2 | Q9UKS7 | 10/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25625082 | 0.85 | IKZF1 (0.43) | IKZF1IKZF2CCR5HDAC1DRD2 | |
| SCHEMBL24791545 | 0.83 | IKZF2 (0.38) | IKZF1IKZF2HDAC1DRD2BTK | |
| SCHEMBL25624857 | 0.81 | IKZF2 (0.42) | IKZF1IKZF2CCR5DRD2 | |
| SCHEMBL25626791 | 0.81 | DRD2 (0.42) | IKZF1IKZF2DRD2 | |
| SCHEMBL24790326 | 0.78 | IKZF1 (0.43) | IKZF1IKZF2CCR5HDAC1DRD2 | |
| SCHEMBL24790789 | 0.76 | IKZF2 (0.35) | IKZF1IKZF2 | |
| SCHEMBL26003966 | 0.75 | MEN1 (0.36) | — | |
| SCHEMBL24789370 | 0.74 | TLR9 (0.33) | IKZF2 | |
| SCHEMBL25625115 | 0.74 | AKT1 (0.36) | IKZF1CCR5HDAC1DRD2 | |
| SCHEMBL27019018 | 0.73 | NPC1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4183782-A1 | 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DI ONE DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2023-05-24 | — | — | EP | disclosed |