Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24791545 | 0.90 | IKZF2 (0.38) | IKZF2DRD2IKZF1 | |
| SCHEMBL25625082 | 0.88 | IKZF1 (0.43) | IKZF2CCR5DRD2IKZF1 | |
| SCHEMBL25616346 | 0.81 | IKZF1 (0.37) | IKZF2CCR5DRD2IKZF1 | |
| SCHEMBL24790875 | 0.81 | PRKAA2 (0.35) | — | |
| SCHEMBL24790326 | 0.81 | IKZF1 (0.43) | IKZF2MAPTCCR5DRD2IKZF1 | |
| SCHEMBL25625115 | 0.80 | AKT1 (0.36) | CCR5DRD2IKZF1 | |
| SCHEMBL27006159 | 0.77 | SDCBP (0.37) | MAPTLMNAKDM4E | |
| SCHEMBL25619901 | 0.77 | IKZF1 (0.35) | CCR5DRD2IKZF1 | |
| SCHEMBL27004983 | 0.77 | ITGB3 (0.36) | MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL27006161 | 0.76 | MAPT (0.41) | MAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4183782-A1 | 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DI ONE DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2023-05-24 | — | — | EP | disclosed |