Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | CCR5 | P51681 | 7/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24790875 | 0.89 | PRKAA2 (0.35) | MCHR1 | |
| SCHEMBL25619901 | 0.88 | IKZF1 (0.35) | DRD2CCR5MEN1KMT2AIKZF1 | |
| SCHEMBL24790325 | 0.83 | DRD2 (0.39) | DRD2CCR5HDAC1KCNH2 | |
| SCHEMBL24790866 | 0.81 | DRD2 (0.39) | DRD2CCR5HDAC1 | |
| SCHEMBL24791545 | 0.81 | IKZF2 (0.38) | DRD2HDAC1IKZF1 | |
| SCHEMBL25625082 | 0.81 | IKZF1 (0.43) | DRD2CCR5HDAC1MEN1KMT2A | |
| SCHEMBL25624857 | 0.80 | IKZF2 (0.42) | DRD2CCR5IKZF1 | |
| SCHEMBL24790272 | 0.80 | IKZF1 (0.35) | DRD2IKZF1 | |
| SCHEMBL24790924 | 0.78 | KDM4E (0.38) | CCR5KMT2A | |
| SCHEMBL24790317 | 0.76 | CACNA2D1 (0.32) | DRD2IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4183782-A1 | 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DI ONE DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2023-05-24 | — | — | EP | disclosed |