Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 6/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891481 | 0.88 | NAMPT (0.36) | THRBGAAPOLBKDM4EALOX15 | |
| SCHEMBL25626791 | 0.88 | DRD2 (0.42) | IKZF2THRBALOX15MAPTLMNA | |
| SCHEMBL25619160 | 0.84 | THRB (0.34) | IKZF2THRBGAAKDM4EALOX15 | |
| SCHEMBL24891345 | 0.83 | THRB (0.34) | THRBGAAPOLBKDM4EALOX15 | |
| SCHEMBL24790237 | 0.82 | HRH3 (0.37) | — | |
| SCHEMBL25624328 | 0.81 | THRB (0.35) | IKZF2THRBGAAPOLBLMNA | |
| SCHEMBL23482963 | 0.80 | MAPT (0.39) | THRBGAAPOLBKDM4EALOX15 | |
| SCHEMBL27316790 | 0.80 | EGFR (0.38) | POLBALDH1A1 | |
| SCHEMBL25615504 | 0.80 | NAMPT (0.41) | IKZF2POLB | |
| SCHEMBL21622035 | 0.79 | NPC1 (0.42) | THRBGAAPOLBKDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672949-B1 | 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2022-12-21 | — | — | EP | disclosed |