Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26982566 | 0.86 | VNN1 (0.37) | VNN1S1PR1LOXL2HCAR2NOS3 | |
| SCHEMBL179254 | 0.80 | KIF11 (0.39) | VNN1LOXL2HCAR2 | |
| SCHEMBL29770233 | 0.80 | S1PR1 (0.43) | VNN1S1PR1LOXL2HCAR2NOS3 | |
| SCHEMBL4926043 | 0.80 | S1PR1 (0.43) | VNN1S1PR1LOXL2HCAR2NOS3 | |
| SCHEMBL19229668 | 0.76 | LOXL2 (0.33) | VNN1LOXL2HCAR2 | |
| SCHEMBL85670 | 0.76 | LOXL2 (0.33) | VNN1LOXL2HCAR2 | |
| SCHEMBL22328432 | 0.73 | NPC1 (0.36) | VNN1LOXL2HCAR2 | |
| SCHEMBL5720526 | 0.72 | HCAR2 (0.41) | S1PR1LOXL2HCAR2 | |
| SCHEMBL2705790 | 0.72 | KIF11 (0.48) | NOS3NOS2 | |
| Chlorobenzene SCHEMBL28481736 | 0.71 | ALDH1A1 (0.41) | VNN1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102100-A1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY (US) | 2023-06-08 | — | — | WO | disclosed |