Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 6/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24790325 | 0.83 | DRD2 (0.39) | IKZF2KCNH2 | |
| SCHEMBL24790866 | 0.82 | DRD2 (0.39) | — | |
| SCHEMBL24790924 | 0.80 | KDM4E (0.38) | IKZF2 | |
| SCHEMBL24789054 | 0.77 | DRD4 (0.32) | — | |
| SCHEMBL24790237 | 0.77 | HRH3 (0.37) | CSF1RCYP3A4 | |
| SCHEMBL25993979 | 0.74 | PRMT5 (0.33) | — | |
| SCHEMBL24790326 | 0.74 | IKZF1 (0.43) | IKZF2IKZF1 | |
| SCHEMBL25982147 | 0.74 | PRMT5 (0.34) | — | |
| SCHEMBL25615504 | 0.74 | NAMPT (0.41) | IKZF2KCNH2 | |
| SCHEMBL24791516 | 0.74 | XIAP (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4183782-A1 | 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DI ONE DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2023-05-24 | — | — | EP | disclosed |