Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24790325 | 0.92 | DRD2 (0.39) | DRD2ADRA1ACCR5HDAC1 | |
| SCHEMBL24790924 | 0.86 | KDM4E (0.38) | CCR5ALDH1A1 | |
| SCHEMBL24790326 | 0.82 | IKZF1 (0.43) | DRD2ADRA1ACCR5HDAC1ALDH1A1 | |
| SCHEMBL25618774 | 0.82 | IKZF2 (0.32) | — | |
| SCHEMBL25625115 | 0.81 | AKT1 (0.36) | DRD2CCR5HDAC1 | |
| SCHEMBL24790875 | 0.81 | PRKAA2 (0.35) | ACHE | |
| SCHEMBL24789054 | 0.81 | DRD4 (0.32) | DRD2 | |
| SCHEMBL24790237 | 0.81 | HRH3 (0.37) | DRD2 | |
| SCHEMBL25619901 | 0.79 | IKZF1 (0.35) | DRD2BCHECCR5ACHE | |
| SCHEMBL25986037 | 0.77 | THRB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672949-B1 | 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2022-12-21 | — | — | EP | disclosed |