SCHEMBL25619019

SCHEMBL25619019

CC1(C)c2ccc3ccccc3c2-c2c(-c3ccccc3)ncnc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.41
AKT1 P31749 1/20 0.36
NPC1 O15118 4/20 0.34
RAB9A P51151 4/20 0.34
MAPT P10636 4/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
JAK2 O60674 1/20 0.34
LMNA P02545 1/20 0.34
RECQL P46063 1/20 0.34
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
PIK3CD O00329 1/20 0.33
PIK3CA P42336 1/20 0.33
PIK3CB P42338 1/20 0.33
MTOR P42345 1/20 0.33
PIK3CG P48736 1/20 0.33
KDM4E B2RXH2 4/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
GPR55 Q9Y2T6 1/20 0.33
CYP19A1 P11511 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18853434 0.81 ADK (0.42) ADORA2ANPC1RAB9AMAPTSMN1; SMN2
SCHEMBL18853464 0.78 ADK (0.40) ADORA2AAKT1NPC1RAB9AMAPT
SCHEMBL18853422 0.78 ADK (0.40) ADORA2AAKT1NPC1RAB9AMAPT
SCHEMBL18853517 0.76 ADK (0.35) NPC1RAB9AMAPTSMN1; SMN2LMNA
SCHEMBL18853598 0.76 GP6 (0.34) NPC1RAB9AMAPTSMN1; SMN2LMNA
SCHEMBL18853560 0.76 ADK (0.35) NPC1RAB9AMAPTSMN1; SMN2LMNA
SCHEMBL18853458 0.76 ADK (0.35) NPC1RAB9AMAPTSMN1; SMN2LMNA
SCHEMBL18853548 0.76 ADK (0.35) NPC1RAB9AMAPTSMN1; SMN2LMNA
SCHEMBL2539931 0.75 CYP2A6 (0.48) RAB9AMAPTLMNARECQLKMT2A
SCHEMBL18853467 0.75 ADK (0.35) NPC1RAB9AMAPTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230200209-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230200209-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230200209-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME CRY1, ZFX, PPOX ADORA2A 4648/4885AKT1 3277/4885NPC1 4659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.