SCHEMBL25620596

SCHEMBL25620596

CCc1ccc(-c2ccc(-c3ccc(OC(C(F)(F)F)(C(F)(F)F)C(F)(F)F)cc3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
KIF11 P52732 1/20 0.39
GRM2 Q14416 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CYP2C19 P33261 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
CYP1A2 P05177 1/20 0.36
RAB9A P51151 1/20 0.36
SLC6A4 P31645 1/20 0.36
PRMT6 Q96LA8 1/20 0.36
PTGER4 P35408 1/20 0.35
MMP2 P08253 1/20 0.35
MMP9 P14780 1/20 0.35
MMP8 P22894 1/20 0.35
SERPINE1 P05121 1/20 0.35
PPARA Q07869 1/20 0.35
CHRNA7 P36544 1/20 0.35
SCN10A Q9Y5Y9 1/20 0.35
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9425434 0.86 TSHR (0.53) TSHRKIF11GRM2ALDH1A1SLC6A4
SCHEMBL2056279 0.86 TSHR (0.53) TSHRKIF11GRM2ALDH1A1SLC6A4
SCHEMBL8990621 0.81 TSHR (0.49) TSHRKIF11GRM2ALDH1A1SLC6A4
SCHEMBL8990856 0.81 TSHR (0.49) TSHRKIF11GRM2ALDH1A1SLC6A4
SCHEMBL155707 0.80 TSHR (0.58) TSHRALDH1A1SLC6A4TP53MAPT
SCHEMBL2098143 0.79 TSHR (0.45) TSHRALDH1A1CYP2C19SMN1; SMN2SLC6A4
Ammonia Solution, Strong SCHEMBL25380785 0.78 TSHR (0.56) TSHRALDH1A1CYP2C19SMN1; SMN2SLC6A4
SCHEMBL13892865 0.76 S1PR1 (0.40) TSHRGRM2ALDH1A1CYP2C19SMN1; SMN2
SCHEMBL9062148 0.75 TSHR (0.53) TSHRALDH1A1SLC6A4TP53MAPT
SCHEMBL2056132 0.75 TSHR (0.53) TSHRALDH1A1SLC6A4MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240217902-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2024-07-04 US disclosed
US-11877508-B2 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2024-01-16 US disclosed
US-20230200214-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2023-06-22 US disclosed
US-20230189636-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2023-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230189636-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF EMC1, EMC2, EPCAM TSHR 3804/4885KIF11 2497/4885GRM2 2411/4885
US-20230200214-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF EMC1, EMC2, EPCAM TSHR 3804/4885KIF11 2497/4885GRM2 2411/4885
US-11877508-B2 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof EMC1, EMC2, EPCAM TSHR 3804/4885KIF11 2497/4885GRM2 2411/4885
US-20240217902-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF EMC1, EMC2, AOC1 TSHR 3926/4885KIF11 2381/4885GRM2 2399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.