Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25622904 | 0.80 | PGK1 (0.31) | TSHRPGK1 | |
| SCHEMBL23264142 | 0.78 | TSHR (0.37) | TSHRCYP1A2CYP2C19 | |
| SCHEMBL3638759 | 0.78 | TLR8 (0.34) | CYP1A2CRHR1 | |
| SCHEMBL501295 | 0.76 | CYP1A2 (0.47) | CYP1A2CRHR1 | |
| SCHEMBL23203443 | 0.74 | LTA4H (0.40) | TSHRCYP2C19 | |
| SCHEMBL23203437 | 0.74 | TSHR (0.39) | TSHRCYP1A2 | |
| SCHEMBL2725593 | 0.71 | TSHR (0.42) | TSHRCYP1A2 | |
| SCHEMBL14420862 | 0.67 | TSHR (0.31) | TSHRCYP1A2 | |
| SCHEMBL2673044 | 0.67 | TSHR (0.39) | TSHR | |
| SCHEMBL1484587 | 0.66 | MAPT (0.33) | TSHRCRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183186-A1 | PYRIMIDINE CYCLOHEXENYL GLUCOCORTICOID RECEPTOR MODULATORS | CORCEPT THERAPEUTICS INCORPORATED | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183186-A1 | PYRIMIDINE CYCLOHEXENYL GLUCOCORTICOID RECEPTOR MODULATORS | NR3C1, NR3C2, MC2R | TSHR 216/4885CYP1A2 1295/4885CRHR1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.