Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | IKZF2 | Q9UKS7 | 10/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25615504 | 0.85 | NAMPT (0.41) | IKZF2POLB | |
| SCHEMBL24790245 | 0.83 | CCR2 (0.33) | THRBGAAIKZF2POLB | |
| SCHEMBL24790326 | 0.83 | IKZF1 (0.43) | IKZF2IKZF1DRD2 | |
| SCHEMBL24790789 | 0.81 | IKZF2 (0.35) | THRBGAAIKZF2POLBLMNA | |
| SCHEMBL25626312 | 0.80 | MAPT (0.36) | THRBGAA | |
| SCHEMBL25620729 | 0.80 | IKZF2 (0.35) | IKZF2IKZF1DRD2 | |
| SCHEMBL24789054 | 0.79 | DRD4 (0.32) | DRD2DRD4DRD3 | |
| SCHEMBL25626791 | 0.79 | DRD2 (0.42) | THRBIKZF2LMNAIKZF1DRD2 | |
| SCHEMBL24790325 | 0.77 | DRD2 (0.39) | IKZF2DRD2DRD4DRD3 | |
| SCHEMBL26024862 | 0.77 | SDCBP (0.42) | THRBGAAPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4183782-A1 | 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DI ONE DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2023-05-24 | — | — | EP | disclosed |