Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25624396 | 0.80 | KDM4E (0.31) | ALDH1A1KDM4EHSD17B10MAPTKMT2A | |
| SCHEMBL12466364 | 0.76 | BAZ2B (0.48) | ALDH1A1SMN1; SMN2LMNABRD4KDM4E | |
| SCHEMBL21809657 | 0.72 | KMT2A (0.37) | ALDH1A1SMN1; SMN2LMNAKDM4EHSD17B10 | |
| SCHEMBL20240764 | 0.69 | LMNA (0.48) | ALDH1A1SMN1; SMN2LMNAKDM4EHSD17B10 | |
| SCHEMBL15026119 | 0.68 | TEAD2 (0.39) | ALDH1A1SMN1; SMN2KDM4EHSD17B10HPGD | |
| SCHEMBL11948593 | 0.68 | KMT2A (0.52) | ALDH1A1LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL1045535 | 0.68 | KMT2A (0.43) | ALDH1A1LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL18149668 | 0.68 | FOS (0.38) | ALDH1A1SMN1; SMN2KDM4EHSD17B10HPGD | |
| SCHEMBL31132618 | 0.67 | GABRA2 (0.38) | ALDH1A1KDM4EHPGDKMT2ACYP1A2 | |
| SCHEMBL15026115 | 0.67 | KDM4E (0.38) | ALDH1A1KDM4EHSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104178-A1 | PROTEIN KINASE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 山东绿叶制药有限公司 | 2023-06-15 | — | — | WO | disclosed |