Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.53 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 2/20 | 0.48 |
| ▸ | CHUK | O15111 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952483 | 0.87 | KDM1A (0.55) | BCAT2MLKLIKBKBCHUKKDM1A | |
| SCHEMBL28201767 | 0.84 | CHUK (0.64) | BCAT2IKBKBCHUKKEAP1PGR | |
| SCHEMBL2561570 | 0.79 | CASP1 (0.62) | BCAT2IKBKBCHUKCASP1KEAP1 | |
| SCHEMBL28203020 | 0.77 | BCAT2 (0.65) | BCAT2IKBKBCHUKKEAP1NFE2L2 | |
| SCHEMBL5878337 | 0.76 | BCAT2 (0.87) | BCAT2IKBKBKEAP1NFE2L2CHEK1 | |
| SCHEMBL30600495 | 0.76 | KDM4E (0.50) | IRAK4 | |
| SCHEMBL5136386 | 0.76 | BCAT2 (0.79) | BCAT2IKBKBCHUKKEAP1NFE2L2 | |
| SCHEMBL6513331 | 0.75 | GRIA4 (0.54) | MLKLKEAP1PGRKDM1A | |
| SCHEMBL30582476 | 0.75 | BCAT2 (0.83) | BCAT2IKBKBCHUKKEAP1NFE2L2 | |
| SCHEMBL28274346 | 0.74 | BCAT2 (0.70) | BCAT2FNTAFNTBCHEK1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382194-A2 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE | RESVERLOGIX CORP. (CA) | 2011-11-02 | — | — | EP | disclosed |