Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 5/20 | 0.64 |
| ▸ | IKBKB | O14920 | 4/20 | 0.64 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.57 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562500 | 0.84 | BCAT2 (0.53) | CHUKIKBKBBCAT2KEAP1PGR | |
| SCHEMBL31610096 | 0.84 | CHUK (0.70) | CHUKIKBKBBCAT2KIF11INSR | |
| SCHEMBL2561570 | 0.82 | CASP1 (0.62) | CHUKIKBKBBCAT2KEAP1HPGD | |
| SCHEMBL5136386 | 0.82 | BCAT2 (0.79) | CHUKIKBKBBCAT2KEAP1BRD4 | |
| SCHEMBL28203020 | 0.81 | BCAT2 (0.65) | CHUKIKBKBBCAT2KEAP1HPGD | |
| Dimethyl Sulfone SCHEMBL28171504 | 0.80 | BCAT2 (0.81) | CHUKIKBKBBCAT2KEAP1HPGD | |
| SCHEMBL5878337 | 0.80 | BCAT2 (0.87) | IKBKBBCAT2KEAP1HPGDKDM4E | |
| SCHEMBL28586126 | 0.80 | BCAT2 (0.62) | CHUKIKBKBBCAT2 | |
| Gsk-586581A SCHEMBL14566310 | 0.79 | IKBKB (1.00) | CHUKIKBKB | |
| SCHEMBL14566187 | 0.79 | IKBKB (0.78) | CHUKIKBKBCSF1RHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107636133-A | The method of lubricating internal combustion engines | 路博润公司 | 2018-01-26 | — | — | CN | disclosed |