⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25627937 | 0.82 | CNR2 (0.30) | — | |
| SCHEMBL25627935 | 0.79 | PIK3CA (0.31) | — | |
| SCHEMBL25613146 | 0.79 | CACNA1G (0.34) | — | |
| SCHEMBL25613148 | 0.79 | KDM4E (0.38) | — | |
| SCHEMBL25613161 | 0.76 | KDM4E (0.40) | — | |
| SCHEMBL25650791 | 0.75 | PIK3CA (0.31) | — | |
| SCHEMBL25613158 | 0.72 | MAP3K11 (0.36) | — | |
| SCHEMBL25613162 | 0.71 | HRH4 (0.37) | — | |
| SCHEMBL25613160 | 0.69 | ALOX15 (0.41) | — | |
| SCHEMBL25613150 | 0.67 | ULK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2023-05-25 | — | — | US | disclosed |