SCHEMBL25627937

SCHEMBL25627937

CC(C)(C)c1cc2ccn(CC(C)(C)c3cc4cc[nH]c4nc3CN3CCNCC3)c2nc1CN1CCOCC1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 1/20 0.30
▸ ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25625249 0.82 — —
SCHEMBL25613160 0.82 ALOX15 (0.41) CNR2ALOX15
SCHEMBL25613158 0.81 MAP3K11 (0.36) —
SCHEMBL25627935 0.77 PIK3CA (0.31) —
SCHEMBL25613161 0.73 KDM4E (0.40) —
SCHEMBL25613148 0.73 KDM4E (0.38) —
SCHEMBL25627230 0.72 HRH4 (0.36) —
SCHEMBL25627088 0.66 ULK1 (0.31) —
SCHEMBL25613151 0.64 PIK3CA (0.49) —
SCHEMBL25613068 0.64 CYP3A4 (0.45) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159527-A1 COMPOUNDS AS BCL-2 INHIBITORS FOCHON BIOSCIENCES, LTD. (CN) 2023-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159527-A1 COMPOUNDS AS BCL-2 INHIBITORS BCL2, BCL2L2, BCL2L1 CNR2 3383/4885ALOX15 2579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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