⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25613101 | 0.84 | JAK2 (0.34) | — | |
| SCHEMBL25627065 | 0.83 | CNR2 (0.31) | — | |
| SCHEMBL25613102 | 0.81 | FEN1 (0.31) | — | |
| SCHEMBL25613110 | 0.79 | JAK2 (0.38) | — | |
| SCHEMBL25613112 | 0.76 | TDP1 (0.35) | — | |
| SCHEMBL25625028 | 0.70 | ALOX5AP (0.36) | — | |
| SCHEMBL25613103 | 0.70 | CHRNA3 (0.42) | — | |
| SCHEMBL24005764 | 0.69 | PIK3CD (0.33) | — | |
| SCHEMBL25613114 | 0.67 | CHRNB4 (0.46) | — | |
| SCHEMBL24005915 | 0.65 | CHRM3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2023-05-25 | — | — | US | disclosed |