SCHEMBL25627065

SCHEMBL25627065

CN1CCOCC1COc1nc2[nH]ccc2cc1C(C)(C)Cn1ccc2cc(C(C)(C)C)c(OCC3CCCN3S(C)(=O)=O)nc21

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25627063 0.83 — —
SCHEMBL25613110 0.81 JAK2 (0.38) CNR2
SCHEMBL25613109 0.80 P2RX3 (0.36) —
SCHEMBL25613101 0.77 JAK2 (0.34) —
SCHEMBL25625028 0.75 ALOX5AP (0.36) CNR2
SCHEMBL25613114 0.74 CHRNB4 (0.46) —
SCHEMBL25613103 0.70 CHRNA3 (0.42) —
SCHEMBL24005745 0.69 SLC6A4 (0.36) —
SCHEMBL25613112 0.67 TDP1 (0.35) —
SCHEMBL25613090 0.67 GRM4 (0.39) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159527-A1 COMPOUNDS AS BCL-2 INHIBITORS FOCHON BIOSCIENCES, LTD. (CN) 2023-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159527-A1 COMPOUNDS AS BCL-2 INHIBITORS BCL2, BCL2L2, BCL2L1 CNR2 3383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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